Ciwon daji na huhu shine nau'in ciwon daji na biyu mafi yawa a duniya. A cikin 2020, fiye da mutane miliyan 2.2 a duniya za su kamu da cutar kansar huhu a karon farko. A cikin wannan shekarar, kimanin mutane miliyan 1.8 a duniya sun mutu sakamakon cutar kansar huhu.
Yayin da a halin yanzu babu magani ga kansar huhu, masana kimiyya suna aiki kan zaɓuɓɓukan magani. Wasu daga cikin wadannan masana kimiyya suna aiki ne a Jami'ar Fasaha ta Sydney (UTS), inda wani sabon bincike ya nuna cewa wani fili na tsire-tsire da ake kira berberine zai iya hana ci gaban kwayoyin cutar kansar huhu a cikin dakin gwaje-gwaje.
Berberine wani fili ne na tsire-tsire da ke faruwa a zahiri wanda aka yi amfani da shi a cikin maganin gargajiya na kasar Sin tsawon dubban shekaru. Ana samunsa a cikin tsire-tsire iri-iri, gami da barberry, goldenseal, innabi na Oregon, da turmeric bishiya.

(samfurin mu shineBerberine Cire, barka da zuwa ga tambaya.)

Shekaru da yawa na bincike sun nuna cewa berberine yana da tasiri wajen taimakawa mutanen da ke da nau'in ciwon sukari na 2 su daidaita matakan sukarin jininsu kuma yana iya taimakawa wajen magance ciwo na rayuwa.
Masu bincike sun kuma gano cewa ana iya amfani da berberine wajen magance cututtukan daji iri-iri, da suka hada da ovarian, ciki, da kuma nono.
A cewar Dokta Kamal Dua, Babban Malami da Babban Jami'in Bincike a Pharmacy a Cibiyar Nazarin Australiya don Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararru na Jami'ar Sydney (UTS) matakai a cikin ci gaban ciwon daji - Yaduwa da ƙaurawar cell.
“A cikin injina, ana iya samun wannan ta hanyar hana manyan kwayoyin halitta irin su P53, PTEN da KRT18 da kuma sunadaran kamar AXL, CA9, ENO2, HER1, HER2, HER3, PRGN, PDGF-AA, DKK1, CTSB, CTSD, BCLX, CSF1. da CAPG da ke da alaƙa da haɓakawa da ƙaura na ƙwayoyin cutar kansa, "in ji shi.
A cikin binciken na yanzu, ƙungiyar bincike da suka haɗa da Dr. Dua, Dokta Keshav Raj Paudel, Farfesa Philip M. Hansbrough da Dokta Bikash Manandhar na UTS, da kuma ma'aikata daga Jami'ar Kiwon Lafiya ta Malaysian International Medical University da Jami'ar Al Qasim a Saudi Arabia. An yi nazarin yadda za a iya amfani da berberine don maganin ciwon huhu.
"Yin amfani da berberine na asibiti yana da iyaka saboda rashin ƙarfi da rashin lafiya," in ji Dokta Dua na MNT. "Babban makasudin wannan binciken shine don inganta sigogi na physicochemical na berberine ta hanyar canza berberine zuwa cikin ruwa crystal nanoparticles da kuma bincika yiwuwar maganin ciwon daji a cikin vitro akan alveolar epithelial basal cell na adenocarcinoma A549."
Ƙungiyar binciken ta haɓaka tsarin isar da magunguna na ci gaba wanda ke tattare da berberine a cikin ƙananan sassa masu narkewa da ƙwayoyin cuta. An yi amfani da waɗannan sinadarai na ruwa crystal nanoparticles don kula da ƙwayoyin cutar kansar huhun ɗan adam a cikin vitro a cikin dakin gwaje-gwaje.
A ƙarshen binciken, ƙungiyar ta gano cewa berberine ya taimaka wajen toshe samar da nau'in oxygen mai amsawa, sinadarai masu kumburi da wasu kwayoyin halitta suka samar don mayar da martani ga mamayewar kwayoyin cuta da sauran abubuwa masu damuwa da zasu iya lalata kwayoyin halitta.
Bugu da kari, berberine yana taimakawa wajen daidaita kwayoyin halittar da ke hade da danniya da kumburi, kuma yana taimakawa rage tsufar kwayar halitta.
"Mun nuna cewa, ta yin amfani da tsarin nanotechnological, za a iya inganta kaddarorin mahallin don magance batutuwa daban-daban da suka shafi solubility, karɓar salula, da kuma maganin warkewa," in ji Dokta Dua. Yiwuwar Ciwon Ciwon Kankara Mu berberine ruwa crystal nanoparticles sun nuna irin wannan aiki a cikin adadin sau biyar idan aka kwatanta da wallafe-wallafen da aka buga, yana nuna fa'idodin nanodrugs a fili.
Don ci gaba da gwada waɗannan sakamakon, Dr. Dua ya ce yana shirin yin amfani da sabon dandalin bincike don gudanar da zurfafa nazari ta hanyar amfani da nau'ikan dabbobi masu kama da cutar kansar huhu.
"Ƙarin nazarin pharmacokinetic da anticancer na berberine nanodrugs a cikin nau'ikan dabbobi a cikin vivo na iya bayyana fa'idodin da suke da shi a cikin maganin ciwon huhu da kuma juya su cikin nau'ikan maganin warkewa," in ji shi.
"Da zarar mun tabbatar da yiwuwar maganin ciwon daji na berberine nanodrugs a cikin nau'in dabba na asali, mataki na gaba zai kasance don matsawa zuwa gwaje-gwaje na asibiti, wanda muka riga muka tattauna da wasu kamfanonin Sydney," in ji Dokta Dua.
Bugu da kari, Dokta Dua ya ce ana bukatar tabbatar da yuwuwar sinadarin berberine na hana sake kamuwa da cutar sankara ta huhu: “Duk da cewa ba mu yi bincike ba tukuna, amma mun shirya yin nazarinsa a nazari na gaba, kuma mun yi imanin cewa berberine nanoforms zai nuna. ayyuka masu ban sha'awa. “.
Dokta Osita Onuga, likitan tiyatar thoracic kuma mataimakiyar farfesa a aikin tiyatar thoracic a Cibiyar Nazarin Cancer ta St. John a Cibiyar Kiwon Lafiya ta Providence St. John da ke Santa Monica, California, ta shaida wa MNT cewa idan masu bincike suka sami sababbin damar yin magani da rigakafin ciwon daji, akwai ko da yaushe. fata:
“Berberine wani bangare ne na magungunan gabas, don haka ba a al’adance mu yi amfani da shi a likitancin kasashen yamma. Ina tsammanin yana da ban sha'awa saboda muna kallon abin da muka sani yana da wasu fa'idodi ga kayan magani na Gabas, kuma sanya shi cikin bincike don taimakawa fassara hakan zuwa likitancin Yamma. “.
"Koyaushe yana da alƙawari, amma yana cikin ɗakin gwaje-gwaje, kuma yawancin abubuwan da muke samu a cikin ɗakin binciken ba lallai ba ne su kai ga jinyar marasa lafiya," Onuga ya ci gaba da cewa. "Ina tsammanin abu na gaba shine yin wasu gwaje-gwaje na asibiti akan marasa lafiya da kuma gano adadin."
Wasu mutane suna fuskantar alamun cutar kansar huhu a farkon cutar. Ci gaba da koyo don ƙarin koyo, gami da lokacin ganin likita.
Ciwon daji na huhu yana faruwa a matakai daban-daban a cikin mata da maza, amma alamun da abubuwan haɗari iri ɗaya ne. Anan mun bayyana yiwuwar kwayoyin halitta da hormonal…
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