Ciwon daji na huhu shi ne nau'in ciwon daji na biyu da aka fi samu a duniya. A shekarar 2020, sama da mutane miliyan 2.2 a duniya za a gano suna da ciwon daji na huhu a karon farko. A wannan shekarar, kimanin mutane miliyan 1.8 ne suka mutu a duniya sakamakon cutar kansar huhu.
Duk da cewa babu maganin cutar kansar huhu a halin yanzu, masana kimiyya suna aiki kan hanyoyin magance ta. Wasu daga cikin waɗannan masana kimiyya suna aiki a Jami'ar Fasaha ta Sydney (UTS), inda wani sabon bincike ya nuna cewa wani sinadari na shuka da ake kira berberine zai iya dakatar da haɓakar ƙwayoyin cutar kansar huhu a cikin dakin gwaje-gwaje.
Berberine wani sinadari ne na shuka da aka samo asali daga halitta wanda aka yi amfani da shi a maganin gargajiya na kasar Sin tsawon dubban shekaru. Ana samunsa a cikin nau'ikan tsire-tsire iri-iri, ciki har da barberry, goldenseal, Oregon innabi, da kuma turmeric na itace.

(Kayanmu shineCirewar Berberine, da gaske maraba da zuwa ga tambaya.)

Shekaru da dama na bincike sun nuna cewa berberine yana da tasiri wajen taimaka wa mutanen da ke fama da ciwon suga na nau'in 2 wajen daidaita matakan sukari a cikin jininsu kuma yana iya taimakawa wajen magance matsalar metabolism.
Masu bincike sun kuma gano cewa ana iya amfani da berberine wajen magance nau'ikan cututtukan daji daban-daban, ciki har da cutar kansar mahaifa, ta ciki, da kuma ta nono.
A cewar Dr. Kamal Dua, Babban Malami kuma Babban Jami'in Bincike a fannin Magunguna a Cibiyar Bincike ta Australiya don Magungunan Haɗin gwiwa da Haɗin gwiwa (ARCCIM), Makarantar Magunguna ta Jami'ar Fasaha ta Sydney (UTS) kuma babban marubucin binciken, Berberine yana hana manyan matakai guda biyu a cikin ci gaban cutar kansa - Yaɗuwa da ƙaura ta ƙwayoyin halitta.
"A zahiri, ana iya cimma wannan ta hanyar hana manyan kwayoyin halitta kamar P53, PTEN da KRT18 da sunadarai kamar AXL, CA9, ENO2, HER1, HER2, HER3, PRGN, PDGF-AA, DKK1, CTSB, CTSD, BCLX, CSF1. da CAPG da ke da alaƙa da yaɗuwa da ƙaurar ƙwayoyin cutar kansa," in ji shi.
A cikin wannan binciken da aka yi, wata ƙungiyar bincike da ta haɗa da Dr. Dua, Dr. Keshav Raj Paudel, Farfesa Philip M. Hansbrough da Dr. Bikash Manandhar na UTS, da kuma ma'aikata daga Jami'ar Likitoci ta Duniya ta Malaysia da Jami'ar Al Qasim da ke Saudiyya, sun yi nazarin yadda ake amfani da berberine wajen magance cutar kansar huhu.
"Amfani da berberine a asibiti yana da iyaka saboda rashin narkewar sa da kuma samuwar sa," in ji Dr. Dua ga MNT. "Babban burin wannan binciken shine inganta sigogin kimiyyar sinadarai na berberine ta hanyar canza berberine zuwa ƙananan ƙwayoyin kristal na ruwa da kuma bincika yuwuwar maganin ciwon daji a cikin vitro akan ƙwayoyin basal na alveolar epithelial na ɗan adam adenocarcinoma A549."
Ƙungiyar binciken ta ƙirƙiro wani ingantaccen tsarin isar da magunguna wanda ke lulluɓe berberine a cikin ƙananan ƙwayoyin halitta masu narkewa da kuma waɗanda za a iya lalata su. An yi amfani da waɗannan ƙwayoyin halittar ruwa don magance ƙwayoyin cutar kansar huhu na ɗan adam a cikin dakin gwaje-gwaje.
A ƙarshen binciken, ƙungiyar ta gano cewa berberine ya taimaka wajen hana samar da nau'ikan iskar oxygen masu amsawa, sinadarai masu kumburi da wasu ƙwayoyin halitta ke samarwa sakamakon mamayewar ƙwayoyin cuta da sauran abubuwan da ke haifar da damuwa waɗanda za su iya lalata ƙwayoyin halitta.
Bugu da ƙari, berberine yana taimakawa wajen daidaita kwayoyin halitta da ke da alaƙa da damuwa da kumburi, kuma yana taimakawa wajen rage tsufan ƙwayoyin halitta kafin lokacin haihuwa.
"Mun nuna cewa, ta amfani da hanyar nanotechnology, ana iya inganta halayen mahaɗin don magance matsaloli daban-daban da suka shafi narkewa, ɗaukar ƙwayoyin halitta, da ingancin magani," in ji Dr. Dua. Damar Maganin Ciwon Daji Nanoparticles ɗinmu na berberine na ruwa sun nuna irin wannan aiki sau biyar idan aka kwatanta da wallafe-wallafen da aka buga, wanda ke nuna fa'idodin nanodrugs a fili."
Domin ƙara gwada waɗannan sakamakon, Dakta Dua ya ce yana shirin amfani da sabon dandalin bincike don gudanar da bincike mai zurfi ta amfani da samfuran dabbobi na cutar kansar huhu kafin a fara amfani da su.
"Ƙarin nazarin magunguna da maganin cutar kansa na ƙwayoyin berberine a cikin samfuran dabbobi a cikin vivo na iya bayyana fa'idodinsu na iya magance cutar kansar huhu da kuma mayar da su zuwa nau'ikan magunguna na warkewa," in ji shi.
"Da zarar mun tabbatar da yuwuwar hana cutar kansar da ke tattare da ƙwayoyin berberine a cikin samfuran dabbobi kafin a fara amfani da su, mataki na gaba zai kasance a koma ga gwaje-gwajen asibiti, wanda muke tattaunawa da wasu kamfanonin Sydney," in ji Dr. Dua.
Bugu da ƙari, Dr. Dua ya ce akwai buƙatar a tabbatar da yuwuwar berberine don hana sake kamuwa da cutar kansar huhu: "Kodayake ba mu bincika wannan ba tukuna, muna shirin yin nazarinsa a cikin nazarin da za a yi nan gaba, kuma muna kuma yi imanin cewa ƙwayoyin berberine nanoforms za su nuna aiki mai kyau.".
Dakta Osita Onuga, likitan tiyatar thoracic kuma mataimakin farfesa na tiyatar thoracic a Cibiyar Ciwon daji ta St. John da ke Cibiyar Kiwon Lafiya ta Providence St. John da ke Santa Monica, California, ta shaida wa MNT cewa lokacin da masu bincike suka sami sabbin damammaki don magancewa da hana cutar kansa, akwai bege koyaushe:
"Berberine wani ɓangare ne na maganin Gabas, don haka ba ma amfani da shi a al'ada a maganin Yammacin Turai. Ina ganin yana da ban sha'awa domin muna duba abin da muka sani yana da wasu fa'idodi ga magungunan Gabas, kuma muna saka shi cikin bincike don taimakawa wajen fassara shi zuwa maganin Yammacin Turai."
"Koyaushe yana da kyau, amma yana cikin dakin gwaje-gwaje, kuma yawancin abin da muke samu a dakin gwaje-gwaje ba lallai bane ya sa a yi wa marasa lafiya magani," in ji Onuga. "Ina ganin abu na gaba da za a yi shi ne a yi wasu gwaje-gwaje na asibiti ga marasa lafiya da kuma gano yawan maganin da za a sha."
Wasu mutane suna fuskantar alamun cutar kansar huhu a farkon matakin cutar. Ci gaba da karatu don ƙarin koyo, gami da lokacin da za a ga likita.
Ciwon daji na huhu yana faruwa a matakai daban-daban a cikin mata da maza, amma alamu da abubuwan da ke haifar da haɗari iri ɗaya ne. A nan mun bayyana yiwuwar kwayoyin halitta da kuma hormones…
Mu ƙwararru ne a fannin ƙera foda na shuka, muna maraba da aiko muku da duk wata tambaya game da samfurinmu kuma muna da abokin aiki mai alhaki don magance matsalolinku game da kafin sayarwa da bayan siyarwa. Tuntuɓe Mu A Kowanne Lokaci!!!