Gabatarwar Citrus Aurantium
Citrus Aurantium, wani tsiro na dangin rutaceae, yana yaduwa a China. Citrus aurantium shine sunan gargajiya na kasar Sin don lemun tsami. A cikin maganin gargajiya na kasar Sin, citrus aurantium ganye ne na gargajiya na gargajiya wanda aka fi amfani da shi don ƙara sha'awa da daidaita qi (makamashi). A Italiya, citrus aurantium kuma ya kasance maganin gargajiya na gargajiya tun ƙarni na 16, ana amfani da shi don magance zazzabi kamar zazzabin cizon sauro da kuma azaman maganin ƙwayoyin cuta. Recent karatu sun nuna cewa citrus aurantium iya maye gurbin ephedra a lura da kiba ba tare da m zuciya da jijiyoyin jini illa.
Abubuwan da ke da tasiri na aurantium citrus sune hesperidin, neohesperidin, nobiletin, auranetin, aurantiamarin, nuringin, synephrine, limonin.
Abu mai aiki
hesperidin, neohesperidin, nobiletin, D-limonene, auranetin, aurantiamarin, citrin, synephrine, limonin.
Dukiyar jiki
Crystallization, narkewar batu 184-1850C, carbonate crystallization 151-152, sauƙi mai narkewa a cikin ruwa. Bitartrate, ma'anar narkewa 188-189, mai narkewa a cikin ruwa, da wuya a narke a cikin ethanol, kusan marar narkewa a cikin chloroform, ether. Hydrochloride, crystal mara launi (ethanol-ethyl ether), wurin narkewa 166-167. Gudun tsere yana da sauƙin faruwa a cikin rarrabuwar chromatography na ƙaƙƙarfan acid da resins na musanya ion tushe.
Pharmacological tasirin
1. Tasiri a cikin mahaifa: Fructus Aurantii da Fructus Aurantii Fructus Decoction daga sassa daban-daban na samarwa (Sichuan, Jiangxi, da Hunan) sun nuna tasirin hanawa a kan mahaifa a cikin vitro na mice (mai ciki da marasa ciki); Ciwon zomo ya yi farin ciki duka a cikin vivo da in vitro (mai ciki kuma ba ciki ba). Har ila yau, yoyon uterine yoyon fitsari ya tabbatar da cewa mahaifar mahaifa yana da ƙarfi, ƙara tashin hankali, har ma da ciwon tetanic. Fructus Aurantii tincture da Fructus Aurantii cirewar ruwa na iya tayar da mahaifar zomo (a cikin vivo da in vitro). Mouse mahaifa (in vitro) an hana shi. Wani abu na alkaloid wanda aka ware daga Fructus Aurantii da Lycium orange shima yana da wani tasiri na kwangila akan mahaifar zomo a cikin vitro, musamman akan tsokar mahaifar da pituitrin ke sha'awar. Bangaren alkaloid da aka cire yana da tasirin shakatawa akan mahaifar zomo a cikin vitro, kuma tasirin shakatawa na mahaifa ya fi bayyane bayan tashin hankali na hypophysial. Cirantin, wanda aka keɓe daga Fructus Aurantii Fructus Peel, yana hana aikin hyaluronate a kusa da ovary, wanda zai iya kasancewa da alaka da maganin hana haihuwa (hana hadi).
2. Tasiri akan hanji: Fructus Aurantii da Fructus Aurantii daga wurare daban-daban guda uku sun hana hanjin cikin beraye da zomaye; Yawancin bututun hanji a cikin zomaye an hana su, amma kaɗan ba su da canji. Fructus Aurantii da tsantsar ruwansa sun hana bututun hanji na beraye (in vitro) da zomaye (in vitro). Babban maida hankali (1: 1000) ya hana ƙananan hanji na zomaye da keɓaɓɓe da aladu na Guinea da kuma hana tasirin acetylcholine da histamine. Ƙananan ƙaddamarwa (1: 10 000), bayan ɗan gajeren lokaci na hanawa, zai iya nuna sakamako mai ban sha'awa, haɓaka girma, da haɓaka mita. A cikin karnukan da aka sawa, kasancewar hanjin an hana shi a fili ta hanyar decoctions. Amma ga karnuka masu gastroenterostomy, yana da wani tasiri mai ban sha'awa, wanda zai iya sa motsin ciki da ƙanƙara mai ƙarfi.
3. Tasiri akan zuciya da tasoshin jini: ƙananan adadin kuzari da babban adadin hanawa a kan zuciyar toad in vitro. Fructus Aurantii da Fructus Aurantii Aurantii Aurantii na ruwa mai ruwa, Fructus Aurantii tincture, da tsantsar ruwa iri ɗaya ne. Fructus Aurantii decoction ko tsantsar barasa da aka yi masa allura ta cikin jini na iya haifar da ingantaccen haɓakar latsawa. Fructus Aurantii da Fructus Aurantii Fructus daga wurare daban-daban guda uku an tabbatar da cewa suna da tasirin vasoconstriction mai sauƙi ta hanyar jijiyar jijiyoyin jiki gaba ɗaya na toads. A cikin karnukan da aka kwantar da su, an sami tasiri mai mahimmanci da saurin hauhawar jini. Babu baƙin ciki na numfashi ko hauhawar jini wanda epinephrine ke haifarwa, kuma babu ƙaramar hauhawar bugun zuciya.
Tsarin haɓaka matsi yana da alaƙa da abubuwa masu zuwa:
3.1. Farin ciki na masu karɓar α, haifar da vasoconstriction a cikin wasu gabobin (phenylzoline na iya juyar da haɓakar matsa lamba a cikin halayen antihypertensive).
3.2. Ingantacciyar ƙaƙƙarfan ƙanƙara na zuciya da ƙara yawan fitarwar zuciya (waɗanda keɓaɓɓen bugun zuciya na alade da shirye-shiryen zuciya). Bayan reserpine, tasirin ƙarfafa matsi na Fructus aurantii aurantii ya fi mahimmanci. Ya haɓaka kwararar jijiyoyin jini sosai (289.4% ya karu da kwararar jijiyoyin jini ta hanyar bubble flowmeter) da haɓaka kwararar jini na kwakwalwa da koda da 86.4% da 64.5% a matsakaici, waɗanda suka bambanta sosai da norepinephrine. An sami raguwar kwararar jini na mata da ɗan ƙaramin ƙarfi amma ƙarancin iskar oxygen na miyocardial, wanda bai zo daidai da haɓakar hauhawar jini ba. A cikin gwaje-gwajen ECG a cikin karnuka da aladu na Guinea, arrhythmia (tachycardia na ventricular ko blockricular block) wanda babban kashi na aurantii aurantii ya haifar ba shi da mahimmanci. Dangane da halayen da ke sama, an ba da shawarar don magance bugun jini na cardiogenic. Alkaloid da aka ware daga Fructus Aurantii da lemu na Lycium suma suna iya haɓaka tashin hankali na tsoka mai santsi na ɗan lokaci, musamman idan aka bi da su tare da pituitrin.
4. Antithrombotic: Gwajin in vitro na 0.1g/ml Fructus Aurantii aqua decoction ya nuna tasirin antithrombotic a fili.
5. Maganin rashin lafiyan jiki: 100mg/kg static pulse injection na Fructus Aurantii Aurantii ruwa tsantsa zai iya hana m fata rashin lafiyan dauki (PCA) a cikin berayen, da kuma 50μg / ml na iya hana histamine saki daga bera na ciki mast Kwayoyin.
6. Sauran illolin: Citrus shuka mycin na iya rage abun ciki na cholestatin a cikin jini da hanta na berayen da ake ciyar da abinci mai dauke da cholesterol. Tushen barasa na Fructus Aurantii yana da tasiri mai hanawa akan mycobacterium tarin fuka H37Rv a cikin vitro, kuma ƙaddamarwar hanawa shine 1:1000. Decoction ɗin sa na ruwa ba shi da wani tasiri akan bronchus alade. An ba da rahoton cewa ruwan 'ya'yan itacen Citrus yana ƙara yawan fermentation na yisti kuma baya rage yawan aiki bayan tafasa, don haka ba wani bangaren enzymatic bane. Babban amfani da ruwan lemu na likitanci shine cewa yana da wadataccen bitamin C kuma yana dauke da adadin bitamin A da B. Bawon ba ya ƙunshi bitamin C amma yana da wadataccen bitamin A. Yana ɗanɗano da ɗaci kuma yana iya ƙarfafa ciki. Yara kamar shan babban adadin kwasfa na iya haifar da guba (ciwon ciki, ciwon ciki).
Dubawa: http://www.a-hospital.com
DominCitrus Aurantium Extract, don Allah a tuntube mu. Muna jiran ku a kowane lokaci !!!
Lokacin aikawa: Dec-15-2022